The Englishman had carded a brilliant 70 to record the only under-par score on day one and he followed that with a 74 to finish level at Mount Juliet Estate, with Spaniard Juan Postigo Arce his closest challenger.
Browne had finished seventh and fourth in the season's two previous events and felt his mental game and his putting were the keys to getting over the line in County Kilkenny.
"It's an amazing feeling," he said.
"I'm on top of the world at the moment, that's how I feel. I don't think it's quite sunk in as to what's going to happen after this for me but I'm absolutely over the moon.
"I've worked on my mental game a lot in the past two or three weeks.
"The game has always been there but on the greens this week, I don't think I had one three-putt, and I holed some nice putts as well so that was key."
After a more than seven-hour delay due to the weather, Browne - ranked seventh in the World Rankings for Golfers with Disability - made bogeys on the first, third and sixth but steadied the ship with back-to-back gains on the ninth and tenth before dropping a shot on the 12th.
"I got off to a very shaky start but I sort of had an inkling what was going on," he said. "I looked at the scoreboard maybe once around the fourth or fifth because I had a few holes to start that weren't so good but I settled down then, got some birdies back and did the job.
"I was very nervous, this is my first time leading such a big event so the nerves got me to start with and then once we settled down the caddie helped me out, thanks to Dave, he's done an amazing job."